In vivo imaging-guided microsurgery based on femtosecond laser produced neo-fluorescent compounds in biological tissues
Posted on 2018-01-11 - 20:07
Femtosecond laser microsurgery has become an advanced method for clinical procedures and biological research. The tissue treated by femtosecond laser can become highly fluorescent, indicating the formation of neo-fluorescent compounds that can naturally label the treated tissue site. We systematically characterized the neo-fluorescence signals produced by femtosecond laser ablation in biological tissues in vivo. Our findings showed that they possess unique fluorescence properties and can be clearly differentiated from endogenous signals and major fluorescent proteins. We further demonstrated that the neo-fluorescent compounds can be used as in vivo labelling agent for biological imaging and guided laser microsurgery.
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Sun, Qiqi; Qin, Zhongya; Wu, Wanjie; Lin, Yue; Chen, Congping; He, Sicong; et al. (2018). In vivo imaging-guided microsurgery based on femtosecond laser produced neo-fluorescent compounds in biological tissues. Optica Publishing Group. Collection. https://doi.org/10.6084/m9.figshare.c.3921124.v1
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AUTHORS (10)
QS
Qiqi Sun
ZQ
Zhongya Qin
WW
Wanjie Wu
YL
Yue Lin
CC
Congping Chen
SH
Sicong He
XL
Xuesong Li
ZW
Zhenguo Wu
YL
Yi Luo
JQ
Jianan Qu