Optica Publishing Group

Low-cost, chromatic confocal endomicroscope for cellular imaging in vivo

Posted on 2021-08-16 - 14:43
We have developed a low-cost, chromatic confocal endomicroscope (CCE) that can image a cross-section of the tissue at cellular resolution. In CCE, a custom miniature objective lens was used to focus different wavelengths into different tissue depths. Therefore, each tissue depth was encoded with the wavelength. A custom miniature spectrometer was used to spectrally-analyze light reflected from the tissue and generate cross-sectional confocal images. The CCE prototype had a diameter of 9.5 mm and a length of 68 mm. Material cost of the CCE prototype was less than $1,500. Measured resolution was high, 2 µm and 4 µm for lateral and axial directions, respectively. Preliminary results showed that CCE can visualize cellular details from cross-sections of the tissue in vivo down to the tissue depth of 100 µm.


3 Biotech
3D Printing in Medicine
3D Research
3D-Printed Materials and Systems
AAPG Bulletin
AAPS PharmSciTech
Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg
ABI Technik (German)
Academic Medicine
Academic Pediatrics
Academic Psychiatry
Academic Questions
Academy of Management Discoveries
Academy of Management Journal
Academy of Management Learning and Education
Academy of Management Perspectives
Academy of Management Proceedings
Academy of Management Review
Select your citation style and then place your mouse over the citation text to select it.



Usage metrics

Biomedical Optics Express


Nachiket Kulkarni
Andrew Masciola
Abhinav Nishant
Kyung-Jo Kim
Heejoo Choi
Arthur Gmitro
Esther Freeman
Aggrey Semeere
Miriam Nakalembe
DongKyun Kang
need help?